Blar i forfatter "Styrvold, Olaf B."

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    • Screening for antibacterial and antifungal activities in marine benthic invertebrates from northern Norway 

      Tadesse, Margey; Gulliksen, Bjørn; Strøm, Morten B.; Styrvold, Olaf B.; Haug, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2008-06-18)
      Benthic marine invertebrates collected from sub-Arctic regions of northern Norway, were found to be a promising source of novel bioactive compounds against human and fish pathogenic bacteria and fungi. Lyophilized material from seven species of ascidians, six sponges and one soft alcyonid coral were extracted with 60% acidified acetonitrile (ACN). After separation into an ACN-rich phase (ACN extract) ...

    • Structure-activity relationships of the antimicrobial peptide arasin 1 - and mode of action studies of the N terminal, proline-rich region 

      Paulsen, Victoria; Blencke, Hans-Matti; Benincasa, Monica; Haug, Tor; Eksteen, Jacobus Johannes; Styrvold, Olaf B.; Scocchi, Marco; Stensvåg, Klara (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Arasin 1 is a 37 amino acid long proline-rich antimicrobial peptide isolated from the spider crab, Hyas araneus. In this work the active region of arasin 1 was identified through structure-activity studies using different peptide fragments derived from the arasin 1 sequence. The pharmacophore was found to be located in the proline/arginine-rich NH2 terminus of the peptide and the fragment arasin ...